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Stay Calm® How It Works References

  1.  Pickering, G. et al. (2020). Magnesium status and stress: the vicious circle concept revisited. Nutrients; 12 (12) :3672. https://pubmed.ncbi.nlm.nih.gov/33260549/
  2. Djokiv, G. et al (2019) The effects of magnesium-melatonin -vitamin B complex in supplementation in treatment of insomnia. Open access maced J Med Sci;7 (18):3101-3105.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6910806/
  3. Cernak, I et al. (2000). Alterations in magnesium and oxidative status during chronic emotional stress. Magnes. Res;13, 29–36.https://pubmed.ncbi.nlm.nih.gov/10761188/
  4. Noah, L. et al. (2021) Effect of magnesium and vitamin B6 supplementation on mental health and quality of life in stressed healthy adults: Post-hoc analysis of a randomised controlled trial. Stress Health;37 (5):1000-1009. https://pubmed.ncbi.nlm.nih.gov/33864354/
  5. Mah, J., & Pitre, T. (2021). Oral magnesium supplementation for insomnia in older adults: A systematic review & meta-analysis. BMC Complementary Medicine and Therapies, 21(1), 1-11. https://pubmed.ncbi.nlm.nih.gov/33865376/
  6. Journal Scientific Opinion on the substantiation of health claims related to pantothenic acid and energy-yielding metabolism (ID 56, 59, 60, 64, 171, 172, 208), mental performance (ID 57), maintenance of bone (ID 61), maintenance of teeth (ID 61), maintenance of hair (ID 61), maintenance of skin (ID 61), maintenance of nails (ID 61) and synthesis and metabolism of steroid hormones, vitamin D and some neurotransmitters (ID 181) pursuant to Article 13(1) of Regulation (EC) No 1924/2006; EFSA Journal 7(10) https://efsa.onlinelibrary.wiley.com/doi/epdf/10.2903/j.efsa.2009.1218
  7. Young, LM. Et al. (2019) A systematic review and meta- analysis of b vitamin supplementation on depressive symptoms, anxiety and stress: Effects on healthy and ‘at-risk’ individuals. Nutrients; 11 (9):2232.https://pubmed.ncbi.nlm.nih.gov/31527485/
  8. Camfield, DA. et al. (2013). The effects of multivitamin supplementation on diurnal cortisol secretion and perceived stress. Nutrients;5(11):4429-50.https://pubmed.ncbi.nlm.nih.gov/24284609/
  9. Panossian, A. and Wikman, G. (2010) Effects of adaptogens on the central nervous system and the molecular mechanisms associated with their stress-protective activity. Pharmaceuticals (Basel); 3 (1) :188-224. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3991026/
  10. Balasubramani, S.P et al. (2011). Plant-based Rasayana drugs from Ayurveda. J. Integr. Med;17(2):88–94. https://pubmed.ncbi.nlm.nih.gov/21390573/
  11. Panossian AG. et al. (2021) Evolution of the adaptogenic concept from traditional use to medical systems: Pharmacology of stress- and aging-related diseases. Med Res Rev;41(1):630-703.https://pubmed.ncbi.nlm.nih.gov/33103257/
  12. What is Ashwagandha -KSM 66® https://ksm66ashwagandhaa.com/ksm-66/what-is-ksm-66/
  13. Chandrasekhar, K. Kapoor, J., & Anishetty, S. (2012) A prospective, randomized double-blind, placebo-controlled study of safety and efficacy of a high-concentration full-spectrum extract of Ashwagandha root in reducing stress and anxiety in adults, Indian journal of psychological medicine; 34(3), 255.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3573577/
  14. Speers, A et al. (2021) Effects of Withania somnifera (Ashwagandha) on Stress and the stress-related neuropsychiatric disorders anxiety, depression, and insomnia. Curr Neuropharmacol; 19 (9):1468-1495.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8762185/
  15. Langade, D. et al. (2019) Efficacy and Safety of Ashwagandha (Withania somnifera) Root Extract in Insomnia and Anxiety: A Double – blind, Randomized, Placebo-controlled study. Cureus, 11(9), e5797.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6827862/
  16. Pratte, M. et al (2014). An alternative treatment for anxiety: a systematic review of human trial results reported for the Ayurvedic herb ashwagandha (Withania somnifera). https://pubmed.ncbi.nlm.nih.gov/25405876/
  17. Ashraf, SA. et al. Cordycepin for Health and wellbeing: a potent bioactive metabolite of an entomopathogenic medicinal fungus Cordyceps with its nutraceutical and therapeutic potential. Molecules;25 (12):2735. https://pubmed.ncbi.nlm.nih.gov/32545666/#:~:text=Cordyceps%20is%20a%20rare%20naturally%20occurring%20entomopathogenic%20fungus,a%20well-known%20medicinal%20mushroom%20in%20traditional%20Chinese%20medicine.
  18. Hirsch KR. et al. (2017). Cordyceps militaris Improves Tolerance to High-Intensity Exercise After Acute and Chronic Supplementation. J Diet Suppl;14(1):42-53.https://pubmed.ncbi.nlm.nih.gov/27408987/
  19. Deng, JS. Et al. (2020) Cordyceps cicadae Mycelia Ameliorate Cisplatin-Induced Acute Kidney Injury by Suppressing the TLR4/NF-κB/MAPK and Activating the HO-1/Nrf2 and Sirt-1/AMPK Pathways in Mice. Oxid Med Cell Longev; 2020:7912763.https://pubmed.ncbi.nlm.nih.gov/32089779/
  20. Kuo, YC. et al. (1996) Cordyceps sinensis as an immunomodulatory agent. Am J Chin med;24 (2):111-25. https://pubmed.ncbi.nlm.nih.gov/8874668/
  21. Olsson EM, von Schéele B and Panossian AG.(2009) A randomised, double-blind, placebo-controlled, parallel-group study of the standardised extract shr-5 of the roots of Rhodiola rosea in the treatment of subjects with stress-related fatigue. Planta Med;75(2):105-12. https://pubmed.ncbi.nlm.nih.gov/19016404/
  22. Ivanova, SE. and Quintela, JC. (2022) The Effectiveness of Rhodiola rosea L. Preparations in Alleviating Various Aspects of Life-Stress Symptoms and Stress-Induced Conditions-Encouraging Clinical Evidence. Molecules;27(12):3902.https://pubmed.ncbi.nlm.nih.gov/35745023/
  23. Agapouda, A. et al. (2022) Rhodiola Rosea Extract Counteracts Stress in an Adaptogenic Response Curve Manner via Elimination of ROS and Induction of Neurite Outgrowth. Oxid Med Cell Longev; 2022:5647599.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9122715/
  24. Yan, T. et al. (2017) Antidepressant-like effects and cognitive enhancement of Schisandra chinensis in chronic unpredictable mild stress mice and its related mechanism. Sci Rep; 7, 6903.https://www.nature.com/articles/s41598-017-07407-1
  25. Park, J.Y and Kim, KH. (2016) A randomized, double-blind, placebo-controlled trial of) Schisandra chinensis for menopausal symptoms. Climacteric, 19:6, 574-580. https://www.tandfonline.com/doi/abs/10.1080/13697137.2016.1238453?journalCode=icmt20
  26. Chan, V. and Lo, K (2022) Efficacy of dietary supplements on improving sleep quality: a systematic review and meta-analysis. BMJ Journals.98 (1158). https://pmj.bmj.com/content/98/1158/285.long
  27. Hidese S. et al. (2019) Effects of L-Theanine Administration on Stress-Related Symptoms and Cognitive Functions in Healthy Adults: A Randomized Controlled Trial. Nutrients; 3;11(10):2362.https://pubmed.ncbi.nlm.nih.gov/31623400/
  28. Evans M. et al (2021). A Randomized, Triple-Blind, Placebo-Controlled, Crossover Study to Investigate the Efficacy of a Single Dose of AlphaWave® L-Theanine on Stress in a Healthy Adult Population. Neurol Ther;10(2):1061-1078.https://pubmed.ncbi.nlm.nih.gov/34562208/
  29. Nobre AC, et al. (2008) L-theanine, a natural constituent in tea, and its effect on mental state. Asia Pac J Clin Nutr;17 Suppl 1:167-168https://pubmed.ncbi.nlm.nih.gov/18296328/
  30. Boyle NB, et al. (2022). A combination of green tea, rhodiola, magnesium and B vitamins modulates brain activity and protects against the effects of induced social stress in healthy volunteers. Nutr Neurosci;25(9):1845-1859.https://pubmed.ncbi.nlm.nih.gov/33896388/
  31. Jongkees BJ. et al.(2015) Effect of tyrosine supplementation on clinical and healthy populations under stress or cognitive demands--A review. J Psychiatr Res. 2015 Nov;70:50-7. https://pubmed.ncbi.nlm.nih.gov/26424423/
  32. National Center for Biotechnology Information (2023). PubChem Compound Summary for CID 6057, Tyrosine. Retrieved March 29, 2023 from https://pubchem.ncbi.nlm.nih.gov/compound/L-tyrosine
  33. Ventura M, Melo M, Carrilho F. (2017) Selenium and Thyroid Disease: From Pathophysiology to Treatment. Int J Endocrinol.;2017:1297658. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5307254/
  34. Turan, E and Karaaslan, O. (2020) The Relationship between Iodine and Selenium Levels with Anxiety and Depression in Patients with Euthyroid Nodular Goiter. Oman Med J;35(4). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7418102/
  35. Scientific Opinion on the substantiation of health claims related to chromium and contribution to normal macronutrient metabolism (ID 260, 401, 4665, 4666, 4667), maintenance of normal blood glucose concentrations (ID 262, 4667), contribution to the maintenance or achievement of a normal body weight (ID 339, 4665, 4666), and reduction of tiredness and fatigue (ID 261) pursuant to Article 13(1) of Regulation (EC) No 1924/2006 https://efsa.onlinelibrary.wiley.com/doi/abs/10.2903/j.efsa.2010.1732
  36. Iyegha, ID.et al. (2019) Associations between poor sleep and glucose intolerance in prediabetes. Psychoneuroendocrinology; 110:104444. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6981225/
  37. Spiegel, K. et al. (2005) Sleep loss: a novel risk factor for insulin resistance and Type 2 diabetes. Journal of Applied Physiology, 99(5), 2008–2019. https://pubmed.ncbi.nlm.nih.gov/16227462/
  38. Durg S, Bavage S and Shivaram SB. (2020) Withania somnifera (Indian ginseng) in diabetes mellitus: A systematic review and meta-analysis of scientific evidence from experimental research to clinical application. Phytother Res;34(5):1041-1059. https://pubmed.ncbi.nlm.nih.gov/31975514/
 

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