Why Brain Fuel is so good

BacoMind^® is a patented, clinically tested and full-spectrum extract of Bacopa Monnieri (Brahmi) with 9 different bioactive compounds, providing a holistic approach to memory and cognitive health support.

With over 20 publications, BacoMind^® was selected for Brain Fuel^® for its safety and efficacy at the therapeutic dose of 300mg, with proven benefits in children, adults and the elderly.

BacoMind^® shows significant improvements in memory recall and retention and supports a reduction in memory disturbance. Significant improvements in learning and memory have been seen with the use of BacoMind^® in children with established learning difficulties.

Among the elderly, clinical trials of BacoMind^® over a 12-week period show an improvement in immediate memory recall of 24%, an improvement of delayed memory recall by 78%, and a reduction in the impact of memory disturbance by 50%.

A 6-month study amongst children between the ages of 6 and 12 years old, showed BacoMind^® helped resolve symptoms of ADHD, “enhancing self-control and attention, while reducing restlessness.” Overall 78% of children in the study exhibited reduced signs of learning difficulties, and 85% showed signs of improved memory. A separate 4 month study carried out on children between the ages of 4 and 18 years old, showed 83% experienced an improved in memory.

References:

BacoMind: The most potent and trusted Bacopa.

Morgan and Stevens.(2010). Does Bacopa monnieri improve memory performance in olderpersons? Results of a randomised, placebo-controlled, double-blind trial.The Journal ofAlternative and Complimentary Medicine;16: 753-759

H.C. Barbhaiyaet al.(2008) Efficacy and tolerability of BacoMind^®on memory improvementin elderly participants-a double blind placebo-controlled study.Journal of Pharmacologyand Toxicology;3:425-434

Usha et al. (2008) BacoMind^®: A Cognitive enhancer in children requiring individualeducation programme. Journal of Pharmacology and Toxicology; 3(4): 302-310

Dave et al.(2014). An open-label study to elucidate the effects of standardised Bacopamonnieri extract in the management of symptoms of attention-deficit hyperactivity disorderin children.Advances in Mind-Body Medicine;28(2):10-5

Peth-Nui, T. et al. (2012) Effects of12-week Bacopa monnieri consumption on attention,cognitive processing, working memory, and functions of both cholinergic andmonoaminergic systems in healthy elderly volunteers.Evid Based Complement AlternatMed; 2012:606424

Kongkeaw, C. et al. (2014). Meta-analysis of randomised controlled trials on cognitiveeffects of Bacopa monnieri extract.J Ethnopharmacol; 151 (1) :528-35

Fatima U. et al. (2022)Pharmacological attributes of Bacopa monnieri extract: Currentupdates and clinical manifestation.Front Nutr;9:972379.

Brain Fuel^® contains essential B Vitamins for your brain health, energy and psychological function, including Vitamin B1, Vitamin B3, Vitamin B5, Vitamin B6 and Vitamin B12. These B Vitamin are in their most bioavailable forms which are more easily absorbed and utilised by the body.

Bacopa Monnieri, Gingko and Turmeric, contain an array of naturally occurring antioxidants that help protect the brain from free radicals which can otherwise cause cell damage. Antioxidants reduce the impact caused by modern living, including any type of stress on the body and mind, such as poor air quality, medications, smoking, processed foods or chemicals found within household products.

Bacopa and Gingko help maintain good cognitive function and memory with age decline. One 12-week randomised controlled study performed with healthy elderly adults, showed Bacopa monnieri improves attention, cognitive processing, and working memory, partly via the suppression of AChE activity. The suppression of the activity of the Acetylcholine enzyme (AChE) means cholinergic function is enhanced, which in turn supports attention and memory processing and gives rise to increased working memory.

Ginkgo helps the maintenance of memory and can play an important role in healthier ageing. Studies also highlight the synergistic effects of ginkgo and turmeric, showing that gingko increases curcumin’s beneficial effects on the brain by raising its brain concentration. The uptake of curcumin into the brain is usually severely limited by its poor ability to cross the blood brain barrier - studies show that ginkgo helps overcome this.

References:

Malik, M. and Tlustos, P. (2023) Nootropic Herbs, Shrubs,and Trees as Potential CognitiveEnhancers. Plant (Basel);12 (6) :1364

Singh et al.(2019). Neuroprotective and Antioxidant Effectof Ginkgo biloba Extract AgainstAD and Other Neurological disorders. Neurotherapeutics; 16(3):666-674

LeeLee KH, Cha M. andLee BH.(2020)Neuroprotective Effect of Antioxidants in the Brain.Int J MolSci;21(19):7152

Assi, AA. et al. (2023) Protective effects of curcumin and Gingko biloba extract incombination on a new model of Alzheimer’s disease. Inflammopharmacology;31 (3) :1449-1464.

Anand, P. et al. (2007). Bioavailability of curcumin: problems and promises. MolPharm; 4(6):807-18

Stough,C.et al.(2001)Neuropsychological changes after 30-day Ginkgo biloba administration in healthy participants.Int. J. Neuropsychopharmacol. ;4:131–134

Wang, Z. (2022). B vitamins and prevention of cognitive decline and incident dementia:systematic review and meta-analysis.Nutr Rev;80 (4):931-949

The combination of Vitamin B5, Bacopa, Ginkgo and Phosphatidylserine have how a powerful effect on improving mental focus and performance, and is one of the early benefits experienced after taking Brain Fuel for 2-3 weeks.

Phosphatidylserine (or 'The Phos' as it's known) is a form of choline and it plays a vital role in the cell-to cell communication in your brain. Scientific research and robust clinical studies show that it exerts a positive impact on the brain’s neurotransmitters, which in turn support focus and concentration.

Gingko Biloba is an extensively researched botanical, acclaimed to support cognitive function and day to day performance tasks such as thinking, reasoning and focusing. Clinical trials show that it plays a role in regulating brain neurotransmitters.

Vitamin B5 contributes to normal mental performance.

Bacopa supports normal blood circulation which in turn supports improved brain performance.

References:

Ma,X. et al. (2022)Phosphatidylserine, inflammation, and central nervous system diseases.Front Aging Neurosci;14:975176

Schreiber S; et al.(2000). An open trial of plant-source derived phosphatidylserine for treatment of age-related cognitive decline.Isr. J. Psychiatry Relat. Sci.37:302–307

B vitamins are essential to gain through diet or supplements because they play a vital role in contributing to brain health, supporting the normal function of the nervous system and optimal daily energy levels.

Vitamins B3, B5, B6 and B12 all contribute to the optimal functioning of your energy metabolism and the reduction of tiredness and fatigue.

Vitamin B6 contributes to red blood cell formation, as well as your protein and glycogen metabolism. Glycogen is the body’s stored form of glucose (i.e sugar) and is the body’s first and preferred form of energy.

Vitamin B12 is provided in the ‘body-ready’ and most easily absorbed 'methylcobalamin' form. Vitamin B12 plays a central role in the control of homocysteine, a primary contributor to the development of cognitive and psychological conditions. B12 also supports the immune system and contributes to the normal functioning of the nervous system. It is a particularly important supplement to take if you are following a vegetarian or vegan diet.

Brain Fuel^® also provides Zinc, an important mineral essential for normal cognitive function, immune support, heathy vision and hormones.

Deficiencies in some B vitamins, in particular Folic acid, Vitamin B6 and B12 have been associated with cognitive decline and impairment. This is due to low levels of these vitamins being associated with high homocysteine levels in the blood, and evidence shows that high homocysteine levels are linked to cardiovascular diseases and cognitive impairment. A deficiency in B12 also is linked to low mood and increased rates of depression.

References:

Sangle P. et al. (2020)Vitamin B12 Supplementation: Preventing Onset and ImprovingPrognosis of Depression.Cureus;12(10):e11169

Hintikka, J. et al. (2003)High vitamin B12 level and good treatment outcome may beassociated in major depressive disorder;3:17